Cyano Acrylate Polymers in Medical Applications
Rajendra P. Pawar, Swapnil R. Sarda, Ravikumar M. Borade, Ashok E. Jadhav, Satish A. Dake and Abraham J. Domb
Affiliation: Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem-91120, Isreal.
Keywords: Cyanoacrylates, polyglycerol sebacate acrylate (PGSA), folate-HNPEGCA-co-HDCA, control multifunctional nano device (CMND'S), fine particle fraction (FPF), actively targetable nanoparticles (ATN)
Cyanoacrylates are solvent free adhesives that cure rapidly when pressed into a thin film between two surfaces. Their ease availability and use in various formulations made them attractive to manufacturers a wide variety of medical devices. Unfortunately, earlier generations of cyanoacrylates had several limitations, such as poor thermal resistance and peel strength. Subsequent developments in cyanoacrylate technology have greatly expanded the performance of these adhesives. This rubber-toughened, surface-insensitive, thermally resistant cyanoacrylate offers advantages over earlier toughened products which has been recently patented. /P >
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