Recent Patents on DNA & Gene Sequences (DIscontinued)

Christian Bronner  
Institute of Genetics and Molecular and Cellular Biology
University of Strasboug


Recent Patents of Gene Sequences Relative to DNA Polymerases

Author(s): Linda J. Reha-Krantz.


Organisms with DNA genomes encode one or more DNA polymerases that are essential enzymes for chromosome replication, DNA repair and recombination. The ability of DNA polymerases to copy DNA templates has been exploited in a variety of in vitro reactions to sequence, amplify, mutate, label and recombine DNA, and in several other applications that are fundamental to molecular biology. Because natural DNA polymerases may have activities that interfere with in vitro applications or their substrate specificity is too narrow, DNA polymerases have been modified for specific applications. Patents are reviewed here on natural and variant DNA polymerases and their uses.

Keywords: DNA polymerases, Variant DNA polymerases, DNA replication, DNA polymerase applications, DNA sequencing, DNA amplification (PCR), DNA recombination, DNA labeling, Mutating DNA, Evolving DNA polymerases

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Article Details

Year: 2008
Page: [145 - 163]
Pages: 19
DOI: 10.2174/187221508786241729
Price: $100