Functions of the HIV-1 Nef Protein

Author(s): Andreas Baur.

Journal Name: Current Drug Targets - Immune, Endocrine & Metabolic Disorders

Volume 4 , Issue 4 , 2004

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Abstract:

The Nef protein of the human immunodeficiency virus is as important for disease progression as it is perplexing in its number of target molecules and functions. In this chapter I will try to give an overview on the numerous functions of HIV from a molecular as well as functional point of view. Due to space restriction and for the sake of clarity I will not describe or list all the effects reported in the literature but rather concentrate on the most important aspects of Nef function.

Keywords: nef, signal transduction, hiv

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Article Details

VOLUME: 4
ISSUE: 4
Year: 2004
Page: [309 - 313]
Pages: 5
DOI: 10.2174/1568005310404040309
Price: $58