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Current Drug Targets - Immune, Endocrine & Metabolic Disorders

Editor-in-Chief

ISSN (Print): 1568-0088
ISSN (Online): 1875-5917

Functions of the HIV-1 Nef Protein

Author(s): Andreas Baur

Volume 4, Issue 4, 2004

Page: [309 - 313] Pages: 5

DOI: 10.2174/1568005310404040309

Price: $65

Abstract

The Nef protein of the human immunodeficiency virus is as important for disease progression as it is perplexing in its number of target molecules and functions. In this chapter I will try to give an overview on the numerous functions of HIV from a molecular as well as functional point of view. Due to space restriction and for the sake of clarity I will not describe or list all the effects reported in the literature but rather concentrate on the most important aspects of Nef function.

Keywords: nef, signal transduction, hiv


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