Abstract
Nanogels of cholesterol-bearing pullulan modified with amino-groups (CHPNH2) were utilized as a career to introduce quantum dots (QDs) into periodontal ligament (PDL) cells. Nanogel-QD effectively labeled PDL cells over 3 weeks. These results indicate that CHPNH2nanogels have a potential as a research tool in the studies of intracellular delivery system.
Keywords: Periodontal ligament cell, intracellular delivery, nanogel, quantum dot, live cell imaging
Drug Metabolism Letters
Title: Intracellular Delivery of Nanogel-Quantum Dot Hybrid Nanoparticles into Human Periodontal Ligament Cells
Volume: 1 Issue: 2
Author(s): Tomoe Fukui, Hiroaki Kobayashi, Urara Hasegawa, Toshiyuki Nagasawa, Kazunari Akiyoshi and Isao Ishikawa
Affiliation:
Keywords: Periodontal ligament cell, intracellular delivery, nanogel, quantum dot, live cell imaging
Abstract: Nanogels of cholesterol-bearing pullulan modified with amino-groups (CHPNH2) were utilized as a career to introduce quantum dots (QDs) into periodontal ligament (PDL) cells. Nanogel-QD effectively labeled PDL cells over 3 weeks. These results indicate that CHPNH2nanogels have a potential as a research tool in the studies of intracellular delivery system.
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Cite this article as:
Fukui Tomoe, Kobayashi Hiroaki, Hasegawa Urara, Nagasawa Toshiyuki, Akiyoshi Kazunari and Ishikawa Isao, Intracellular Delivery of Nanogel-Quantum Dot Hybrid Nanoparticles into Human Periodontal Ligament Cells, Drug Metabolism Letters 2007; 1 (2) . https://dx.doi.org/10.2174/187231207780363570
DOI https://dx.doi.org/10.2174/187231207780363570 |
Print ISSN 1872-3128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1874-0758 |
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