Abstract
Gene therapy or recombinant DNA vaccines targeting multiple antigenic components to direct empower the immune system. Antigenic epitopes on neurotoxin Mesobuthus martensii (Buthus martensii) are important determinant of protection against cardiovascular disorder. Small segments 4-YSSDCRVKCVAM-15, 18-SSGKCINSKC-27 of neurotoxin protein called the antigenic epitopes is sufficient for eliciting the desired immune response. In analysis predicted antigenic epitopes neurotoxin protein is seen. Immunization cassettes should be capable of immunizing of broad immunity against both humoral and cellular epitope thus giving vaccines the maximum ability to deal with neurotoxin protein of M. martensii. We have predicted a successful immunization.
Keywords: Neurotoxin, antigenic epitope, GOR, hydrophobicity, hydrophilicity
Current Drug Discovery Technologies
Title: Prediction of Antigenic Epitopes of Neurotoxin Bmbktx1 from Mesobuthus martensii
Volume: 3 Issue: 3
Author(s): Virendra S. Gomase
Affiliation:
Keywords: Neurotoxin, antigenic epitope, GOR, hydrophobicity, hydrophilicity
Abstract: Gene therapy or recombinant DNA vaccines targeting multiple antigenic components to direct empower the immune system. Antigenic epitopes on neurotoxin Mesobuthus martensii (Buthus martensii) are important determinant of protection against cardiovascular disorder. Small segments 4-YSSDCRVKCVAM-15, 18-SSGKCINSKC-27 of neurotoxin protein called the antigenic epitopes is sufficient for eliciting the desired immune response. In analysis predicted antigenic epitopes neurotoxin protein is seen. Immunization cassettes should be capable of immunizing of broad immunity against both humoral and cellular epitope thus giving vaccines the maximum ability to deal with neurotoxin protein of M. martensii. We have predicted a successful immunization.
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Cite this article as:
Gomase S. Virendra, Prediction of Antigenic Epitopes of Neurotoxin Bmbktx1 from Mesobuthus martensii, Current Drug Discovery Technologies 2006; 3 (3) . https://dx.doi.org/10.2174/157016306780136817
DOI https://dx.doi.org/10.2174/157016306780136817 |
Print ISSN 1570-1638 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6220 |
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