Synthesis of 3-Aroylcoumarin-Flavone Hybrids

Author(s): Hulluru S.P. Rao, Venkata S. Tangeti.

Journal Name: Letters in Organic Chemistry

Volume 9 , Issue 3 , 2012

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A facile two step synthesis of 3-aroylcoumarin-flavone hybrids was achieved from 7-hydroxyflavone and α- oxoketene dithioacetals. In the first step 7-hydroxyflavone was regioselectively formylated under Duff reaction conditions. Resulting 8-formyl-7-hydroxy flavones were condensed with α-oxoketene dithioacetals in the presence of a catalytic amount of piperidine to furnish 3-aroylcoumarin-flavone hybrids.

Keywords: 7-hydroxyflavone, α-oxoketene dithioacetal, 8-formyl-7-hydroxy flavones, coumrain-flaovone hybrid, duff reaction, coumarins, fluorescent, flavones, sensitizers, carbonyls

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Article Details

Year: 2012
Page: [218 - 220]
Pages: 3
DOI: 10.2174/157017812800167501
Price: $65

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