Alkyne-Azide Cycloaddition Catalyzed by Fe-Cu Nanoparticles

Author(s): Angel Garcia-Munoz, Jaime Gonzalez, Jessica Trujillo-Reyes, Raul A. Morales-Luckie, Victor Sanchez-Mendieta, Carlos Gonzalez, Aydee Fuentes, Erick Cuevas-Yanez.

Journal Name: Letters in Organic Chemistry

Volume 9 , Issue 3 , 2012

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1,2,3-triazoles were synthesized using several alkynes and azides as starting materials in the presence of catalytic amounts of Cu-Fe nanoparticles. The process represents many advantages because it does not require additional bases or reductants, and this is carried out under ambient pressure and temperature with good yields.

Keywords: 1,2,3-triazoles, alkynes, azides, nanoparticles, CuAAC, phenylacetylene, cycloaddition, bromide, sodium, aqueous mixture

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Article Details

Year: 2012
Page: [160 - 164]
Pages: 5
DOI: 10.2174/157017812800167457
Price: $58

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