Current Stem Cell Research & Therapy

Anthony Atala  
Wake Forest University School of Medicine,
Medical Center Boulevard
Winston Salem, NC 27157


Biodegradable Bone Regeneration Synthetic Scaffolds: in Tissue Engineering

Author(s): Salah Hammouche, Dalia Hammouche, Michael McNicholas.


A growing array of synthetic bone regeneration scaffolds has been used or investigated over the last century. These scaffolds aim to provide a three dimensional substrate for bone cells to populate on and function appropriately. To serve this function, these scaffolds should be biocompatible and biodegradable at a rate commensurate with bone remodelling. Their mechanical properties should also be similar to those of the bone regeneration site. In this review, the main families of synthetic bone scaffolds were taxonomised and expounded. The main focus of this paper will be on the basic sciences principles and properties of clinical available as well as experimental synthetic bone scaffolds. Special emphasis was put on scaffolds developed over the last ten years.

Keywords: Bone regeneration, osteoconductivity, osteoinductivity, scaffold, tissue engineering, cartilage repair, OSTEOARTHRITIS, EMBRYOLOGY OF CARTILAGE, ARTICULAR CARTILAGE

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Article Details

Year: 2012
Page: [134 - 142]
Pages: 9
DOI: 10.2174/157488812799219018
Price: $58