The Use of Glucose as Alternative Reducing Agent in Copper-Catalyzed Alkyne-Azide Cycloaddition

Author(s): Marco A. Garcia, Zita G. Rios, Jaime Gonzalez, Víctor M. Perez, Nancy Lara, Aydee Fuentes, Carlos Gonzalez, David Corona, Erick Cuevas-Yanez.

Journal Name: Letters in Organic Chemistry

Volume 8 , Issue 10 , 2011

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Abstract:

1,2,3-triazoles were synthesized using several alkynes and azides as starting materials in the presence of glucose and catalytic amounts of Fehling reagent. This process is carried out under ambient pressure and temperature with good yields

Keywords: Alkynes, azides, Fehling reagent, glucose, 1,2,3-triazoles, copper, pressure, temperature, triazole, sodium

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Article Details

VOLUME: 8
ISSUE: 10
Year: 2011
Page: [701 - 706]
Pages: 6
DOI: 10.2174/157017811799304232
Price: $58

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