Title: Development of Sugar-Based Materials for Biological Devices
VOLUME: 12 ISSUE: 3
Author(s):Yuji Mikata and Shigenobu Yano
Affiliation:KYOUSEI Science Center, Nara Women's University, Kitauoyanishimachi, Nara 630-8506, Japan.
Keywords:Carbohydrates, metal, porphyrin, nucleic acids, biological activity of the complex, macrocycles, β-lactams, β-C-glycosylation, bioactive molecules, metal complexes, peptide synthesis, anomeric oxygen atoms, peptide-based drug candidates, apical atoms
Abstract: Recent progresses of our group dealing with newly developed sugar-based ligands and their metal complexes have been reviewed. Carbohydrate moiety affects on the stereochemistry around the metal center and controls the biological activity of the complex.