Development of Sugar-Based Materials for Biological Devices

Author(s): Yuji Mikata, Shigenobu Yano.

Journal Name: Current Topics in Medicinal Chemistry

Volume 12 , Issue 3 , 2012

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Abstract:

Recent progresses of our group dealing with newly developed sugar-based ligands and their metal complexes have been reviewed. Carbohydrate moiety affects on the stereochemistry around the metal center and controls the biological activity of the complex.

Keywords: Carbohydrates, metal, porphyrin, nucleic acids, biological activity of the complex, macrocycles, β-lactams, β-C-glycosylation, bioactive molecules, metal complexes, peptide synthesis, anomeric oxygen atoms, peptide-based drug candidates, apical atoms

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Article Details

VOLUME: 12
ISSUE: 3
Year: 2012
Page: [145 - 157]
Pages: 13
DOI: 10.2174/156802612799079017
Price: $58

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