Caffeic Acid, A Versatile Pharmacophore: An Overview

Author(s): M. Touaibia, J. Jean-Francois, J. Doiron.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 11 , Issue 8 , 2011

Abstract:

The caffeic acid scaffold, which is abundant in nature, is extremely versatile and is found in a number of biologically active molecules. The purpose of this review is to provide an overview of the pharmacological activity of synthetic caffeic acid analogs including recent reports of anti-inflammatory, anti-cancer, and antiviral activities of these compounds.

Keywords: Caffeic acid, anticancer, antioxidant, anti-inflammatory, integrase inhibitors, structure-activity relationships, Pharmacophore, scaffold, natural products, antiviral, synthetic caffeic acid

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 11
ISSUE: 8
Year: 2011
Page: [695 - 713]
Pages: 19
DOI: 10.2174/138955711796268750
Price: $58

Article Metrics

PDF: 33