Synthesis and Biological Properties of Dihydro-Oxadiazine-Based Heterocyclic Derivatives

Author(s): S. Ke, X. Cao, Y. Liang, K. Wang, Z. Yang.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 11 , Issue 8 , 2011

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Abstract:

Dihydro-oxadiazine and its derivatives have been demonstrated to be important heterocyclic scaffold platform with bioactive diversity, which present wide activities such as cardiovascular, antitumor, antibacterial, antimicrobial, acricidal, insecticidal, plant-growth regulating, chitin biosynthesis inhibitors and monoamine oxidase inhibition. Versatile features of dihydro-oxadiazine heterocycles have emerged, so the aim of the present paper was to review the recent advances of dihydro-oxadiazine-based heterocyclic derivatives mainly including synthesis and biological activities.

Keywords: Dihydro-oxadiazine, heterocycle, synthesis, biological activity, heterocyclic scaffold, cardiovascular, antitumor, antibacterial, antimicrobial, acricidal, insecticidal, plant-growth regulating, chitin biosynthesis, monoamine oxidase

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Article Details

VOLUME: 11
ISSUE: 8
Year: 2011
Page: [642 - 657]
Pages: 16
DOI: 10.2174/138955711796268769
Price: $58

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