Atherosclerotic Renal Artery Stenosis: An Update on Diagnosis and Management

Eirini      Stavrinou; Charalambos      Koumaras; Thomas      D. Gossios; Konstantinos      Tziomalos; Vasilios      G. Athyros; Asterios      Karagiannis

Abstract

Atherosclerotic renal artery stenosis (ARAS) is a progressive disease and it is usually associated with hypertension as well as with chronic kidney and cardiovascular disease. Although the anatomical lesions are relatively easy to depict, there is need to identify diagnostic methods to establish the functional significance of the stenosis and predict the response to revascularization. Over the last years, renal revascularization appears to be increasingly performed in patients with ARAS. However, controversy abounds as so far prospective, randomised trials did not document any benefit of revascularization with or without stenting plus optimal medical treatment over optimal medical treatment alone. In this review, we discuss the current data in the field of diagnosis and management of patients with ARAS

Keywords: Atherosclerotic renal artery stenosis, renovascular hypertension, diagnosis, management, renal revascularization, cardiovascular disease, coronary heart disease, type 2 diabetes mellitus, aortic aneurysm, angiotensin receptor blocker