Stem Cell-Mediated Delivery of Therapies in the Treatment of Glioma

Author(s): G. Frosina.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 11 , Issue 7 , 2011

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Abstract:

High grade gliomas can be seldom controlled, due to the infiltrative nature of these tumors and the presence of cell populations resistant to radio- and chemotherapy. Current research aims to develop novel therapeutic approaches to track and eliminate the disseminated glioma-driving cells. Selected delivery of therapeutic agents taking advantage of the tropism of normal stem cells for glioma cells might be one.

Keywords: Glioma, stem, gene therapy, cancer, resistance, High grade, ADSC, bone morphogenetic protein, cytosine deaminase, cyclophosphamide, connexin 43, EGF, ganciclovir, mesenchymal stem cell

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Article Details

VOLUME: 11
ISSUE: 7
Year: 2011
Page: [591 - 598]
Pages: 8
DOI: 10.2174/138955711795906897
Price: $58