Chiral Lewis Acid Catalysis in Water

Author(s): Chikako Ogawa, Shu Kobayashi.

Journal Name: Current Organic Synthesis

Volume 8 , Issue 3 , 2011

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The progress of development in chiral Lewis acid catalyzed reaction in water is described. Lewis acid surfactant-combined catalyst and chiral bipyridine ligand complex realized catalytic asymmetric hydroxymethylation and ring-opening reaction in water successfully. Furthermore, silica-supported Lewis acid catalyst was applied for asymmetric hydroxylation in water.

Keywords: Aldol reaction, Chiral Lewis acid, Epoxide, Green chemistry, Lewis acid, Mannich reaction, Water, asymmetric, organic, solvents

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Article Details

Year: 2011
Page: [345 - 355]
Pages: 11
DOI: 10.2174/157017911795529119
Price: $58

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