Current Pediatric Reviews

Giuseppe Buonocore
Department of Molecular and Developmental Medicine
University of Siena


Pierre Robin Sequence

Author(s): Jack C. Yu, Renee Hilton, R. Gerry Magana.


This is a mini-review of the etiopathogenesis and management of Pierre Robin Sequence (PRS). PRS is the combination of intermittent upper airway obstruction, glossoptosis, microgenia, and retrognathia, with or without cleft palate. 70 to 75% of PRS babies can be managed by prone positioning. Failing conservative measures, classified as Caouette-Laberge Group III PRS patients, surgical airway management is necessary and includes tongue-lip adhesion, mandibular distraction, or tracheostomy. The objectives are to provide a comprehensive, practical, and updated synopsis for health care professionals involved in the care of this group of patients, so that accurate diagnosis can be made, logical treatment plan can be formulated, and effective therapy can be carried out. Particular emphasis is placed on the management for Group III patients with focus on the technical aspects of the tongue-lip adhesion and distraction osteogenesis in this review.

Keywords: Distraction osteogenesis, pierre robin sequence, tongue lip adhesion, glossoptosis, microgenia, retrognathia

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Article Details

Year: 2011
Page: [15 - 19]
Pages: 5
DOI: 10.2174/157339611795429035