Current Rheumatology Reviews

Dr. Serena Guiducci  
Department of Biomedicine, Division of Rheumatology
University of Florence


Epidemiology of Gout: Perspectives from the Past

Author(s): Hallie R. Buckley.


Gout is an ancient disease with a prevalence that has increased dramatically worldwide over recent years. This paper briefly reviews the recent literature on the frequency of gout and geographic variation in contemporary populations and attempts to provide a synthesis of reported cases of gout in the past. The palaeopathological evidence of gout in the Asia Pacific region is focussed on and the biocultural context of food and ritual influencing the selection of hyperuricaemia is discussed. It is proposed that the prehistoric selection pressures leading to the high prevalence of diabetes and other ‘diseases of modernisation’ may also, at least in part, explain the high frequencies of hyperuricaemia and gout in modern Pacific Islanders.

Keywords: Gout, epidemiology, palaeopathology, Pacific Islands, thrifty genotype, hyperuricaemia, palaeoepidemiology, osteoblastic, spondyloarthropathies, osteopaenia

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Article Details

Year: 2011
Page: [106 - 113]
Pages: 8
DOI: 10.2174/157339711795305022
Price: $58