A mild and efficient iodine-catalyzed direct substitution of hydroxy group of allylic, progargylic and other alcohols with various C- and N-nucleophiles was described in this contribution. C-C and C-N bond formations could be readily achieved by non-metallic and green catalysis for various compounds. This facilitates access to possible transformations of a broad scope of substrates into bioactive and pharmaceutically important building blocks.
Keywords: Allylation, Bond formation, C-, N-nucleophiles, Green chemistry, Iodine, Isomerization, Propargylation, Substitution
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