Synthesis of N1- and N8-(γ -L-Glutamyl)spermidines and (γ -L-Glutamyl) putrescine

Author(s): Kazuya Toho , Naoki Abe , Teiko Yamada , Yoshifumi Ito , Hiroyuki Konno , Shigefumi Kuwahara , Hiromasa Kiyota .

Journal Name: Letters in Organic Chemistry

Volume 8 , Issue 1 , 2011

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Abstract:

(γ-L-Glutamyl)putrescine and N1- and N8-(γ-L-glutamyl)spermidines, possible regioisomeric products of the polyamine glutamyl transferase of bacteria such as Escherichia coli and Pseudomonas aeruginosa, were synthesized from N-Boc-protected putrescine and 1,3-propanediamine.

Keywords: glutamylspermidine, glutamylputrescine, Pseudomonas aeruginosa, polyamine biosynthesis, polyamine glutamyl transferase

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Article Details

VOLUME: 8
ISSUE: 1
Year: 2011
Page: [1 - 4]
Pages: 4
DOI: 10.2174/157017811794557813

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