Mono- and Bis-2-amino-4H-pyrans: Alum Catalyzed Three- or Pseudo Five-Component Reaction of 4-Hydroxycoumarin, Malononitrile and Aldehydes

Author(s): Ali Reza Karimi, Cyrus Eslami.

Journal Name: Letters in Organic Chemistry

Volume 8 , Issue 2 , 2011

Become EABM
Become Reviewer


An efficient method for the three- or pseudo five-component synthesis of mono- and bis-2-amino-4H-pyrans in excellent yields using Alum (KAl(SO4)2.12H2O) as recyclable catalyst is described. The present methodology offers several advantages such as excellent yields, simple procedures, shorter reaction times, milder conditions and the catalysts exhibited remarkable reusable activity.

Keywords: Alum (KAl(SO4)2.12H2O), 2-Amino-4H-pyrans, 4-Hydroxycoumarin, 1,4-dihydropyridines, triethylamine, aldehydes, aminophosphonates, malononitrile, Spectrophotometer, nitrobenzaldehyde

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2011
Page: [150 - 154]
Pages: 5
DOI: 10.2174/157017811794697421
Price: $58

Article Metrics

PDF: 3