α-Hydroxyiminophosphonate, -phosphinate and -phosphonium Derivatives

Author(s): Javier Vicario, Concepcion Alonso, Jesus M. de los Santos, Francisco Palacios.

Journal Name: Current Organic Synthesis

Volume 7 , Issue 6 , 2010

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Abstract:

The structural and synthetic aspects related to α-oxyiminophosphorus derivatives are reviewed. This includes their preparation through reactions involving C-N double bond or P-C single bond formation as well as the O-functionalization or transformations at the phosphorus atom of other phosphorus substituted oximes. Moreover the synthetic features of α-oxyiminophosphorus derivatives include the reduction of the oximo group with selective preparation of biologically active α-amino-phosphonate and -phosphinate derivatives, as well as the oxidative transformations on the oxime group, rearrangement versus fragmentation reactions, radical reactions and formation of metal complexes.

Keywords: Iminophosphonates, iminophosphinates, iminophosphonium salts, aminophosphonic acids, Beckmann rearrangement

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Article Details

VOLUME: 7
ISSUE: 6
Year: 2010
Page: [628 - 649]
Pages: 22
DOI: 10.2174/157017910794328583
Price: $58

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