Metal Triflates: Efficient Catalysts for Oxa-Pictet-Spengler Reaction

Title: Metal Triflates: Efficient Catalysts for Oxa-Pictet-Spengler Reaction

Volume: 7 Issue: 6

Author(s): Benaissa Bouguerne, Christian Lherbet and Michel Baltas

Affiliation:

Keywords: Metal triflate, oxa-Pictet-Spengler, catalysis

Abstract: A screening of different metal triflates as catalysts was performed to get isochromans through an oxa-Pictet- Spengler reaction. Good to high yields were obtained for various aliphatic or aromatic aldehydes and β-arylethanols. A mechanism involving catalysis by in situ liberated triflic acid to catalyse the isochroman ring formation is proposed.

Cite this article as:

Bouguerne Benaissa, Lherbet Christian and Baltas Michel, Metal Triflates: Efficient Catalysts for Oxa-Pictet-Spengler Reaction, Letters in Organic Chemistry 2010; 7 (6) . https://dx.doi.org/10.2174/157017810791824883