Giardiasis, Drug Resistance, and New Target Discovery

Author(s): Hai-Feng Tian, Bing Chen, Jian-Fan Wen.

Journal Name: Infectious Disorders - Drug Targets
(Formerly Current Drug Targets - Infectious Disorders)

Volume 10 , Issue 4 , 2010

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Abstract:

Giardiasis is a worldwide parasitic disease caused by the protozoan Giardia lamblia in humans and other animals, especially live stocks. Here, we briefly review the current state of therapeutic availability for giardiasis, including chemical drugs and vaccines, and the dilemma in the prevention and treatment of this disease, including the emergence of drug resistance and the shortage of vaccine (especially for humans). Future efforts and progress in controlling giardiasis are expected in three aspects: clarification of the drug resistance mechanisms, development of efficient vaccines, and identification of more targets for new drugs and vaccines.

Keywords: Giardia lamblia, giardiasis, drug resistance, vaccine, target

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Article Details

VOLUME: 10
ISSUE: 4
Year: 2010
Page: [295 - 302]
Pages: 8
DOI: 10.2174/187152610791591629
Price: $58

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