A New Method of Reducing 2-Mercapto-Substituted 1,3,4-Oxadizoles: Synthesis of Acylhydrazine Derivatives

Title: A New Method of Reducing 2-Mercapto-Substituted 1,3,4-Oxadizoles: Synthesis of Acylhydrazine Derivatives

Volume: 7 Issue: 5

Author(s): Muhammad Zareef, Rashid Iqbal, Javid Hussain Zaidi, Muhammad Arfan, Muhammad Ali and Khalid M. Khan

Affiliation:

Keywords: Acylhydrazine derivatives, benzenediazasulfonamide, 1,3,4-oxadiazole, sodium acytoxyborohydride

Abstract: A new method has been developed for the synthesis of acylhydrazines 5a-g by the reduction of unsymmetrical 1,3,4-oxadiazoles 4a-g by using sodium borohydride/acetic acid combination. Later on, acylhydrazines 5a-g were converted to their corresponding sulfonamide derivatives 6a-d.

Cite this article as:

Zareef Muhammad, Iqbal Rashid, Hussain Zaidi Javid, Arfan Muhammad, Ali Muhammad and M. Khan Khalid, A New Method of Reducing 2-Mercapto-Substituted 1,3,4-Oxadizoles: Synthesis of Acylhydrazine Derivatives, Letters in Organic Chemistry 2010; 7 (5) . https://dx.doi.org/10.2174/157017810791514670