A New Method of Reducing 2-Mercapto-Substituted 1,3,4-Oxadizoles: Synthesis of Acylhydrazine Derivatives

Author(s): Muhammad Zareef, Rashid Iqbal, Javid Hussain Zaidi, Muhammad Arfan, Muhammad Ali, Khalid M. Khan.

Journal Name:Letters in Organic Chemistry

Volume 7 , Issue 5 , 2010

Abstract:

A new method has been developed for the synthesis of acylhydrazines 5a-g by the reduction of unsymmetrical 1,3,4-oxadiazoles 4a-g by using sodium borohydride/acetic acid combination. Later on, acylhydrazines 5a-g were converted to their corresponding sulfonamide derivatives 6a-d.

Keywords: Acylhydrazine derivatives, benzenediazasulfonamide, 1,3,4-oxadiazole, sodium acytoxyborohydride

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Article Details

VOLUME: 7
ISSUE: 5
Year: 2010
Page: [411 - 414]
Pages: 4
DOI: 10.2174/157017810791514670
Price: $58

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