Letters in Drug Design & Discovery

G. Perry
University of Texas
San Antonio, TX
USA
Email: lddd@benthamscience.org

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Synthesis and Anticoccidial Activity of 3-(2-(1-methoxynaphthalen-2-yl)-2-oxoethyl) Quinazolinone Derivatives

Author(s): Yuanyuan Zhang, Guangmin Chen, Yabiao Weng, Renliang Li, Yuliang Wang, Yuzhong Wang.

Abstract:

A series of 3-(2-(1-methoxynaphthalen-2-yl)-2-oxoethyl) quinazolinone derivatives (8a-k) were designed and synthesized. Their anticoccidial activities were evaluated against Eimeria tenella in vivo. The results indicated that compounds 8a, 8b and 8e exhibited anticoccidial activity against Eimeria tenella in the chickens diet with a dose of 18 mg/Kg.

Keywords: 3-(2-(1-methoxynaphthalen-2-yl)-2-oxoethyl) quinazolinone, Derivatives, Synthesis, Anticoccidial activity, Eimeria tenella

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Article Details

VOLUME: 7
ISSUE: 6
Year: 2010
Page: [471 - 475]
Pages: 5
DOI: 10.2174/157018010791306498
Price: $58