Current Stem Cell Research & Therapy

Anthony Atala  
Wake Forest University School of Medicine,
Medical Center Boulevard
Winston Salem, NC 27157
USA

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Periodontal Disease and Periodontal Tissue Regeneration

Author(s): Morikuni Tobita, Hiroshi Mizuno.

Abstract:

Periodontal disease leads to destruction of the periodontium such as alveolar bone, cementum, the periodontal ligament, and gingiva. Effective treatment for periodontal tissue regeneration is important, because periodontal disease is related to several systemic diseases. However, various conventional therapies for periodontal tissue regeneration have shown limited and variable clinical outcomes. Thus, there are ongoing efforts to identify an alternative cell source, such as stem cells, for the development of new tissue engineering therapies. In this review, periodontal disease and the application of tissue engineering for periodontal tissue regeneration are discussed. In particular, adipose-derived stem cells are presented as an agent for restoring periodontal tissue defects.

Keywords: Adipose-derived stem cells, periodontal disease, periodontal tissue regeneration, tissue engineering, mesenchymal stem cells, fat tissue

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Article Details

VOLUME: 5
ISSUE: 2
Year: 2010
Page: [168 - 174]
Pages: 7
DOI: 10.2174/157488810791268672
Price: $58