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Current Stem Cell Research & Therapy
ISSN (Print): 1574-888X
ISSN (Online): 2212-3946
VOLUME: 5
ISSUE: 2
DOI: 10.2174/157488810791268555      Price:  $58









Characterization of Adipose-Derived Stem Cells: An Update

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Author(s): Alexander M. Bailey, Sahil Kapur and Adam J. Katz
Pages 95-102 (8)
Abstract:
Adipose tissue is an attractive source of multipotent adult stem cells due to its wide-spread availability, accessibility, and ease of harvest. Adipose-derived stem cells (ASCs), the adherent stromal cell population present within adipose tissue, are easily expanded in culture, able to differentiate along multiple cell-lineage pathways, and have been shown to provide therapeutic benefit in models of injury and disease through immunomodulation, structural integation, and/or trophic support. Recent developments in the characterization of ASCs, specifically their isolation, gene and protein expression, differentiation, and expansion, are reviewed in this article.
Keywords:
Characterization, isolation, donor variability, expansion, adipose-derived stem cell, stromal cell
Affiliation:
Department of Plastic Surgery, University of Virginia, P.O. Box 800376, Charlottesville, VA 22908, USA.