The preparation and use of Animal Bone Meal (ABM) as natural catalyst is described for C-S bond formation by thia-Michael addition. This new natural heterogeneous method led to β-sulfinyl adducts in very high yields after only a few minutes. Influence of the thiol derivatives and substitution on chalcones is discussed.
Keywords: Bones, animal bone meal, michael addition, chalcones, thiols, α,β-unsaturated ketones, X-Ray analysis
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