Non-Invasive Approaches to Visualize the Endothelin Axis In Vivo Using State-of-the-Art Molecular Imaging Modalities

Author(s): C. Holtke, A. Faust, H-J. Breyholz, K. Kopka, O. Schober, B. Riemann, C. Bremer, M. Schafers, S. Wagner.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 9 , Issue 14 , 2009

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Abstract:

The endothelin (ET) axis plays a major role in cardiovascular diseases and a number of human cancers. This review summarizes the work that has been published in the past ten years using labeled endothelin receptor ligands for the visualization of endothelin receptor expression in vivo.

Keywords: Molecular imaging, endothelin axis, tumor angiogenesis, endothelial dysfunction, cardiovascular diseases

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Article Details

VOLUME: 9
ISSUE: 14
Year: 2009
Page: [1580 - 1595]
Pages: 16
DOI: 10.2174/138955709791012210
Price: $58

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