An Improved Process for the Production of Rivastigmine Tartrate, a Cholinesterase Inhibitor

Author(s): Vajrala Venkata Reddy, Mandava Venkata Naga Brahmeswara Rao, Varanasi Ganesh, Adla Vijaya Kumar, Cherukupally Praveen, Khagga Mukkanti, Ganta Mahesh Reddy, Ganta Madhusudhan Reddy.

Journal Name: Letters in Organic Chemistry

Volume 7 , Issue 2 , 2010

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An improved and scalable process for the production of rivastigmine tartrate is reported. The improved process provides rivastigmine tartrate at considerably lower cost and allows the omission of hazardous chemicals. The overall yield is increased from 4.66% (reported process) to 17% with the improved process.

Keywords: Rivastigmine tartrate, a cholinesterase inhibitor, alzheimer's disease, improved process, impurities

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Article Details

Year: 2010
Page: [149 - 154]
Pages: 6
DOI: 10.2174/157017810790796246
Price: $58

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PDF: 10