Iron Trichloride Catalyzed One-Pot Synthesis of Substituted Oxazoles from Propargylic Acetates and Amides under Microwave Irradiation

Author(s): Wen-Wen Xu , Min Lin , Yang Huang , Li Chen , Zhuang-Ping Zhan .

Journal Name: Letters in Organic Chemistry

Volume 6 , Issue 8 , 2009

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Abstract:

A rapid and efficient procedure under microwave irradiation, using silica gel-supported reagents for the synthesis of substitued oxazoles has been developed through iron trichloride catalyzed propargylation/cycloisomerization tandem reaction of propargylic acetates and amides.

Keywords: Iron trichloride, oxazole, microwave irradiation

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Article Details

VOLUME: 6
ISSUE: 8
Year: 2009
Page: [664 - 668]
Pages: 5
DOI: 10.2174/157017809790442970
Price: $58

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