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Current Topics in Medicinal Chemistry
ISSN (Print): 1568-0266
ISSN (Online): 1873-5294
VOLUME: 9
ISSUE: 16
DOI: 10.2174/156802609789909795      Price:  $58









Low Molecular Weight and Oligomeric Chitosans and Their Bioactivities

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Author(s): Heng Yin, Yuguang Du and Junzeng Zhang
Pages 1546-1559 (14)
Abstract:
Chitosan is one of the most abundant marine-based biopolymers. Low molecular weight and oligomeric chitosans are water-soluble hydrolysates of chitosan. They have been shown to have a wide range of biological activities and industrial applications. In particular, low molecular weight and oligomeric chitosans have been reported to have the health benefits such as immunity regulation, anti-tumor, liver protection, blood lipids lowering, anti-diabetic, antioxidant and anti-obesity. In this paper, the preparation and analytical methods, and bioactivities of these low molecular weight and oligomeric chitosans were reviewed, with the latest progresses introduced and discussed.
Keywords:
Low molecular weight chitosan (LMWC), chitosan oligosaccharide (COS), preparation, analytical method, bioactivity
Affiliation:
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning 116023, China.