Current Topics in Medicinal Chemistry

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
USA

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Low Molecular Weight and Oligomeric Chitosans and Their Bioactivities

Author(s): Heng Yin, Yuguang Du, Junzeng Zhang.

Abstract:

Chitosan is one of the most abundant marine-based biopolymers. Low molecular weight and oligomeric chitosans are water-soluble hydrolysates of chitosan. They have been shown to have a wide range of biological activities and industrial applications. In particular, low molecular weight and oligomeric chitosans have been reported to have the health benefits such as immunity regulation, anti-tumor, liver protection, blood lipids lowering, anti-diabetic, antioxidant and anti-obesity. In this paper, the preparation and analytical methods, and bioactivities of these low molecular weight and oligomeric chitosans were reviewed, with the latest progresses introduced and discussed.

Keywords: Low molecular weight chitosan (LMWC), chitosan oligosaccharide (COS), preparation, analytical method, bioactivity

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Article Details

VOLUME: 9
ISSUE: 16
Year: 2009
Page: [1546 - 1559]
Pages: 14
DOI: 10.2174/156802609789909795
Price: $58