Current Topics in Medicinal Chemistry

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA


Anticancer Drugs Discovery and Development from Marine Organisms

Author(s): Chiranjib Chakraborty, Chi-Hsin Hsu, Zhi-Hong Wen and Chan-Shing Lin

Affiliation: Department of Marine Biotechnology and Resources, College of Marine Science and Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohisung, Taiwan.

Keywords: Anticancer drugs discovery, marine families and evolution, marine biodiversity


The chemical and biological diversity of the different marine evolutionary group is endless and therefore, this is an amazing resource for the discovery of new anticancer drugs. Comprising 34 of the 36 Phyla of life, marine ecosystems are indeed our last genetic diversity and biotechnological boundary; terrestrial systems possess only 17 Phyla. Sponges, coelenterates and microorganisms are the foremost resources of therapeutic compounds. Algae, echinoderms, tunicates, mollusks, bryozoans are also the sources of anticancer drugs from marine resources. We highlight the past and current status of marine anticancer pharmacology using different marine groups.

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Article Details

Page: [1536 - 1545]
Pages: 10
DOI: 10.2174/156802609789909803