Current Topics in Medicinal Chemistry

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
USA

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Anticancer Drugs Discovery and Development from Marine Organisms

Author(s): Chiranjib Chakraborty, Chi-Hsin Hsu, Zhi-Hong Wen, Chan-Shing Lin.

Abstract:

The chemical and biological diversity of the different marine evolutionary group is endless and therefore, this is an amazing resource for the discovery of new anticancer drugs. Comprising 34 of the 36 Phyla of life, marine ecosystems are indeed our last genetic diversity and biotechnological boundary; terrestrial systems possess only 17 Phyla. Sponges, coelenterates and microorganisms are the foremost resources of therapeutic compounds. Algae, echinoderms, tunicates, mollusks, bryozoans are also the sources of anticancer drugs from marine resources. We highlight the past and current status of marine anticancer pharmacology using different marine groups.

Keywords: Anticancer drugs discovery, marine families and evolution, marine biodiversity

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Article Details

VOLUME: 9
ISSUE: 16
Page: [1536 - 1545]
Pages: 10
DOI: 10.2174/156802609789909803
Price: $58