Crystal Structure of Bucain, a Three-Fingered Toxin from the Venom of the Malayan Krait (Bungarus candidus)

Author(s): M. T. Murakami, R. M. Kini, R. K. Arni.

Journal Name: Protein & Peptide Letters

Volume 16 , Issue 12 , 2009

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Abstract:

Bucain, a potent neurotoxin isolated from the venom of the Malayan krait (Bungarus candidus), induces paralysis and death. Its crystal structure has been determined at 2.10 A resolution and based on the molecular topology and hydrophobicity profile is structurally classified as a three-fingered α-neurotoxin possessing a positively charged AChR-binding site.

Keywords: Bucain, crystal structure, Bungarus candidus, three-finger α-neurotoxin

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Article Details

VOLUME: 16
ISSUE: 12
Year: 2009
Page: [1473 - 1477]
Pages: 5
DOI: 10.2174/092986609789839304
Price: $58

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