The Pilot Phase of the NIH Chemical Genomics Center

Author(s): Craig J. Thomas, Douglas S. Auld, Ruili Huang, Wenwei Huang, Ajit Jadhav, Ronald L. Johnson, William Leister, David J. Maloney, Juan J. Marugan, Sam Michael, Anton Simeonov, Noel Southall, Menghang Xia, Wei Zheng, James Inglese, Christopher P. Austin.

Journal Name: Current Topics in Medicinal Chemistry

Volume 9 , Issue 13 , 2009

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Abstract:

The NIH Chemical Genomics Center (NCGC) was the inaugural center of the Molecular Libraries and Screening Center Network (MLSCN). Along with the nine other research centers of the MLSCN, the NCGC was established with a primary goal of bringing industrial technology and experience to empower the scientific community with small molecule compounds for use in their research. We intend this review to serve as 1) an introduction to the NCGC standard operating procedures, 2) an overview of several of the lessons learned during the pilot phase and 3) a review of several of the innovative discoveries reported during the pilot phase of the MLSCN.

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Article Details

VOLUME: 9
ISSUE: 13
Year: 2009
Page: [1181 - 1193]
Pages: 13
DOI: 10.2174/156802609789753644
Price: $58

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