Recent Patents on CNS Drug Discovery (Discontinued)

Vincenzo Di Marzo
Istituto di Chimica Biomolecolare (I.C.B.)
Consiglio Nazionale delle Ricerche (C.N.R.)
Via Campi Flegrei 34
Pozzuoli, Napoli 80078


New Frontiers in Alcoholism and Addiction Treatment

Author(s): Felice Nava, Andrea Vendramin, Ezio Manzato, Mauro Cibin, Alfio Lucchini.


Drug addiction and alcoholism are behavioural disorders characterized by a profound alteration of several brain circuits induced by chronic drug use. Their treatment is yet based on empiricism and today only few pharmacological strategies are fully effective to control both drug use and relapse. The present paper reviews the most updated pharmacotherapies able to contrast both alcoholism and drug addiction including the new patented drugs and the future therapeutic trends.

Keywords: Alcoholism, addiction, buprenorphine, methadone, suboxone®, naltrexone, gamma-hydroxybutyrrate, nociceptin peptide receptors, CB1 cannabinoid receptors, dopamine

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Article Details

Year: 2010
Page: [81 - 94]
Pages: 14
DOI: 10.2174/157488910789753567