Abstract
In a Nature article published in 1993, Anthony L. Fink and colleagues reported how Hsp70 chaperones use ATP binding in the presence of K+, rather than hydrolysis, to accelerate substrate release. As of the summer of 2008, his article had received 297 citations. I discuss here the influence Tonys iconic article has had on the chaperone field.
Keywords: Chaperone, heat shock protein, unfolded protein, ATPase
Current Protein & Peptide Science
Title: The Fink Blueprint for Hsp70/Hsc70 Molecular Chaperones
Volume: 10 Issue: 5
Author(s): Stephan N. Witt
Affiliation:
Keywords: Chaperone, heat shock protein, unfolded protein, ATPase
Abstract: In a Nature article published in 1993, Anthony L. Fink and colleagues reported how Hsp70 chaperones use ATP binding in the presence of K+, rather than hydrolysis, to accelerate substrate release. As of the summer of 2008, his article had received 297 citations. I discuss here the influence Tonys iconic article has had on the chaperone field.
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Cite this article as:
Witt N. Stephan, The Fink Blueprint for Hsp70/Hsc70 Molecular Chaperones, Current Protein & Peptide Science 2009; 10 (5) . https://dx.doi.org/10.2174/138920309789352047
DOI https://dx.doi.org/10.2174/138920309789352047 |
Print ISSN 1389-2037 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5550 |
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