Current Women`s Health Reviews

John Yeh  
Harvard Medical School 
Department of Obstetrics and Gynecology
Massachusetts General Hospital
Boston, MA


The Clinics and Etiology of Preeclampsia

Author(s): Christianne A.R. Lok, Rienk Nieuwland, Kees Boer, Augueste Sturk, Joris A.M. Van Der Post.


Preeclampsia is a trophoblast-induced disorder of pregnancy with characteristics of a multisystem disease, resulting from an adverse maternal response to (in part) allogenic placental tissue. Preeclampsia is a heterogeneous disorder. Therefore, generalization of results from different studies is difficult and clear definitions are essential. The exact etiology of preeclampsia is still a matter of debate and many theories have been proposed. It is unlikely that a single factor underlies the development of preeclampsia. This review describes definitions of hypertensive disorders in preeclampsia and summarizes the most important pathophysiologic mechanisms.

Keywords: Preeclampsia, hypertension, etiology, definition

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Article Details

Year: 2009
Page: [157 - 166]
Pages: 10
DOI: 10.2174/157340409789007268
Price: $58