Forms of Iron Binding in the Cells and the Chemical Features of Chelation Therapy

Author(s): S. Puntarulo , M. Galleano .

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 9 , Issue 9 , 2009

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Abstract:

Iron is essential for human life, however it can be toxic through Fe ability to generate oxygen-derived radicals. This work reviews the main features of Fe binding in the cell and its association to these processes. The chemical nature of the Fe extracted by chelation therapy in pathophysiological situations is also analyzed.

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Article Details

VOLUME: 9
ISSUE: 9
Year: 2009
Page: [1136 - 1146]
Pages: 11
DOI: 10.2174/138955709788922674
Price: $58

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