The Use of Intravenous Aminobisphosphonates for the Treatment of Pagets Disease of Bone

Author(s): Luigi Gennari, Daniela Merlotti, Giuseppe Mossetti, Domenico Rendina, Vincenzo De Paola, Giuseppe Martini, Ranuccio Nuti.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 9 , Issue 9 , 2009

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Abstract:

Pagets disease of bone is a focal skeletal disorder characterized by the formation of structurally abnormal bone, deformity and other complications leading to significant disability and bone pain. Recently, the availability of newer, more potent nitrogen-containing bisphosphonates has improved treatment outcomes, allowing a more effective and convenient management of this disorder.

Keywords: Paget's disease of bone, bone turnover, bisphosphonates, zoledronic acid, pamidronate, neridronate

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Article Details

VOLUME: 9
ISSUE: 9
Year: 2009
Page: [1052 - 1063]
Pages: 12
DOI: 10.2174/138955709788922683
Price: $58

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