Human- and Virus-Encoded microRNAs as Potential Targets of Antiviral Therapy

Author(s): Anna Kurzynska-Kokorniak , Paulina Jackowiak , Magdalena Figlerowicz , Marek Figlerowicz .

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 9 , Issue 8 , 2009

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Abstract:

It has recently been demonstrated that short RNA molecules, called microRNAs, are one of the major factors regulating the expression of human genes. There are several lines of evidence that microRNAs also play a key role in host-virus interactions. It is believed that both human- and virus-encoded miRNA will, in the nearest future, become very attractive targets of antiviral therapy.

Keywords: microRNA, host-virus interaction, antiviral therapy, antagomiR, miRNA mimetic, target protector, artificial miRNA

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Article Details

VOLUME: 9
ISSUE: 8
Year: 2009
Page: [927 - 937]
Pages: 11
DOI: 10.2174/138955709788681573
Price: $58

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