Solid-Phase Synthesis of 2-Iodomethyl-2,3-dihydrobenzofurans Using Recyclable Polymer-Supported Selenium Bromide

Author(s): Shouri Sheng, Minggang Hu, Dan Wu, Mingzhong Cai, Xian Huang.

Journal Name: Letters in Organic Chemistry

Volume 6 , Issue 4 , 2009

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Reaction of polymer-supported selenium bromide with ortho allylated phenols and subsequent cleavage from the polymer by treatment of methyl iodide efficiently afforded 2-iodomethyl-2,3-dihydrobenzofurans in good yields and high purities. The polymeric reagent can be regenerated and reused as environmentally friendly reagent.

Keywords: Solid-phase organic synthesis, Polymer-supported selenium bromide, Recyclable, Selenium mediated intramolecular cyclization, 2-Iodomethyl-2,3-dihydrobenzofuran, Traceless cleavage

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Article Details

Year: 2009
Page: [345 - 348]
Pages: 4
DOI: 10.2174/157017809788489837
Price: $65

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