Solid-Phase Synthesis of 2-Iodomethyl-2,3-dihydrobenzofurans Using Recyclable Polymer-Supported Selenium Bromide

Author(s): Shouri Sheng, Minggang Hu, Dan Wu, Mingzhong Cai, Xian Huang.

Journal Name: Letters in Organic Chemistry

Volume 6 , Issue 4 , 2009

Become EABM
Become Reviewer

Abstract:

Reaction of polymer-supported selenium bromide with ortho allylated phenols and subsequent cleavage from the polymer by treatment of methyl iodide efficiently afforded 2-iodomethyl-2,3-dihydrobenzofurans in good yields and high purities. The polymeric reagent can be regenerated and reused as environmentally friendly reagent.

Keywords: Solid-phase organic synthesis, Polymer-supported selenium bromide, Recyclable, Selenium mediated intramolecular cyclization, 2-Iodomethyl-2,3-dihydrobenzofuran, Traceless cleavage

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 6
ISSUE: 4
Year: 2009
Page: [345 - 348]
Pages: 4
DOI: 10.2174/157017809788489837
Price: $65

Article Metrics

PDF: 3