Memory-Enhancing Drugs: A Molecular Perspective

Author(s): Barbara Monti, Antonio Contestabile.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 9 , Issue 7 , 2009

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Abstract:

Neurodegenerative diseases associated with dementia are characterized by cognitive deficits and memory impairment, thus stimulating research for memory enhancing drugs. We survey here the state of the art of research and clinical trials on these drugs from cholinesterase inhibitors and drugs acting on neurotransmitter receptors to drugs acting on gene expression.

Keywords: Memory, neurodegenerative disease, acetylcholine, AMPA receptor, CREB, chromatin

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Article Details

VOLUME: 9
ISSUE: 7
Year: 2009
Page: [769 - 781]
Pages: 13
DOI: 10.2174/138955709788452621
Price: $58

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