A Novel Biginelli-Like Reaction: An Efficient One-pot Synthesis of Spiro[oxindole-quinazoline/pyrimidine]ones

Author(s): Hassan Kefayati, Kurosh Rad-Moghadam, Masoumeh Zamani, Sanaz Hosseyni.

Journal Name: Letters in Organic Chemistry

Volume 7 , Issue 4 , 2010

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Abstract:

Some new spiro[oxindole-quinazoline/pyrimidine]ones were synthesized via a novel three-component Biginelli-like reaction between isatin, cyclic or acyclic 1,3-dicarbonyl compounds, and urea, N-methyl urea or thiourea in one pot and good yields.

Keywords: Quinazolinone, pyrimidinone, spiro oxindole, multi-component reaction, Biginelli-like reaction, isatin

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Article Details

VOLUME: 7
ISSUE: 4
Year: 2010
Page: [277 - 282]
Pages: 6
DOI: 10.2174/157017810791130577
Price: $65

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