Solid-Supported Ammonium Fluorides in Organic Synthesis

Author(s): F. Fringuelli, D. Lanari, F. Pizzo, L. Vaccaro.

Journal Name: Current Organic Synthesis

Volume 6 , Issue 2 , 2009

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Abstract:

The use of fluoride ion as a base and nucleophile has been widely exploited in organic synthesis. On the other hand over the last few decades the fast-growing development of polymer supported reagents has led to the synthesis of a variety of fluorides on solid support. Such compounds display some major benefits: i.e they are less hygroscopic, easy to recover and to recycle. Tetraalkylammonium fluorides represent some of the most common available sources of fluoride, their solid-supported analogues have been employed in a large range of organic reactions.

Keywords: Tetraalkylammonium fluoride, solid-supported organo catalyst, polymer-supported fluoride, ion-exchange resin, amberlyst A-26 fluoride form

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Article Details

VOLUME: 6
ISSUE: 2
Year: 2009
Page: [203 - 218]
Pages: 16
DOI: 10.2174/157017909788167284
Price: $58

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