Title: Neonatal Persistent Pulmonary Hypertension Associated with Congenital Cystic Adenomatoid Malformation Treated with Sildenafil: Case Report
VOLUME: 5 ISSUE: 2
Author(s):Gianfranco Maffei, Vincenzo Manuppelli and Rosario Magaldi
Affiliation:Neonatal Intensive Care Unit, “Ospedali Riuniti”, Foggia Hospital, S N L Pinto STR., Foggia, 71100, Italy.
Keywords:PPHN, CCAM, sildenafil, HFOV, oxygenation index
Abstract: We report a case with severe persistent pulmonary hypertension (PPHN) associated with congenital cystic adenomatoid malformation of the lung (CCAM) treated with sildenafil PO. The case was unresponsive to the High-Frequency Oscillatory Ventilation (HFOV), with a oxygenation index (OI) of 50 before sildenafil. Substantial improvement in OI was followed by extubation and survival. No side-effects were noted.
