Abstract
Alveolar capillary dysplasia (ACD) is a recently recognized lethal lung malformation. ACD is a rare congenital disorder of pulmonary vascular development associated with unremitting hypoxemia and respiratory failure. This paper reviews the incidence, pathophysiology and histopathology, clinical manifestations, diagnosis, and treatment of affected newborns and proposes an algorithmic approach to management of infants who present with unremitting persistent pulmonary hypertension of the newborn.
Keywords: Newborn, alveolar capillary dysplasia, pulmonary hypertension, extracorporeal membrane oxygenation
Current Respiratory Medicine Reviews
Title: Alveolar Capillary Dysplasia: A Lethal Developmental Lung Malformation
Volume: 5 Issue: 2
Author(s): Aaron W. Swenson and Steven M. Donn
Affiliation:
Keywords: Newborn, alveolar capillary dysplasia, pulmonary hypertension, extracorporeal membrane oxygenation
Abstract: Alveolar capillary dysplasia (ACD) is a recently recognized lethal lung malformation. ACD is a rare congenital disorder of pulmonary vascular development associated with unremitting hypoxemia and respiratory failure. This paper reviews the incidence, pathophysiology and histopathology, clinical manifestations, diagnosis, and treatment of affected newborns and proposes an algorithmic approach to management of infants who present with unremitting persistent pulmonary hypertension of the newborn.
Export Options
About this article
Cite this article as:
Swenson W. Aaron and Donn M. Steven, Alveolar Capillary Dysplasia: A Lethal Developmental Lung Malformation, Current Respiratory Medicine Reviews 2009; 5 (2) . https://dx.doi.org/10.2174/157339809788189950
DOI https://dx.doi.org/10.2174/157339809788189950 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
Call for Papers in Thematic Issues
Exposure to PM2.5 components is associated with respiratory diseases
Through continuous research on the relationship between risk factors and health, it has been found that air pollution, especially atmospheric particulate matter pollution, has become one of the main sources of global disease burden. From 1990 to 2022, the concentration of atmospheric particulate matter pollution has increased by more than ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Diabetic Heart and the Cardiovascular Surgeon
Cardiovascular & Hematological Disorders-Drug Targets Latest Results for Anti-Angiogenic Drugs in Cancer Treatment
Current Pharmaceutical Design Protective Effects of Diuretics Against the Development of Cardiovascular Disease in Patients with Chronic Kidney Disease: A Systematic Review
Cardiovascular & Hematological Agents in Medicinal Chemistry Quercetin-Phospholipid Complex: An Amorphous Pharmaceutical System in Herbal Drug Delivery
Current Drug Discovery Technologies Recent Patents on Ocular Drug Delivery Systems
Recent Patents on Drug Delivery & Formulation Disorders of Respiration and Sleep-Disordered Breathing in Patients with Chronic Renal Failure
Current Respiratory Medicine Reviews An Overview of Compounds Derived from the Shikimate and Phenylpropanoid Pathways and Their Medicinal Importance
Mini-Reviews in Medicinal Chemistry Subject Index To Volum 2
Current Diabetes Reviews Combination of Statin Plus Renin Angiotensin System Inhibition for the Prevention or the Treatment of Atherosclerotic Cardiovascular Disease
Current Pharmaceutical Design “Self-Nonself” Peptides in the Design of Vaccines
Current Pharmaceutical Design <i>In silico</i> Approach for Exploring the Role of AT1R Polymorphism on its Function, Structure and Drug Interactions
Current Computer-Aided Drug Design The Role of PPARs in Pathological Cardiac Hypertrophy and Heart Failure
Current Pharmaceutical Design Effects of Quercetin against Mycotoxin Induced Cytotoxicity: A Mini- Review
Current Nutrition & Food Science Monitoring Calcific Aortic Valve Disease: The Role of Biomarkers
Current Medicinal Chemistry Soy Isoflavones and Cardiovascular Health: An Update
Current Nutrition & Food Science Endogenous Ligand Bias by Chemokines: Implications at the Front Lines of Infection and Leukocyte Trafficking
Endocrine, Metabolic & Immune Disorders - Drug Targets Abnormal Peri-Organ or Intra-organ Fat (APIFat) Deposition: An Underestimated Predictor of Vascular Risk?
Current Vascular Pharmacology Therapeutic Approaches of Leptin in Alzheimers Disease
Recent Patents on CNS Drug Discovery (Discontinued) Molecular Basis of Cardioprotection by Erythropoietin
Current Molecular Pharmacology Oxidative Stress Targeting Amyloid Beta Accumulation and Clearance in Alzheimer’s Disease: Insight into Pathological Mechanisms and Therapeutic Strategies
Current Psychopharmacology