Importance of a Potential Salt Bridge and Hydrophobic Core in the Function and Oligomerization of a Small Heat Shock Protein

Title: Importance of a Potential Salt Bridge and Hydrophobic Core in the Function and Oligomerization of a Small Heat Shock Protein

VOLUME: 17 ISSUE: 6

Author(s):Zhenzhen Wen, Yonghua Wang, Xun Xu, Bo Yang, Wencheng Li and Mingquan Xie

Affiliation:From School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510640, China.

Keywords:Small heat shock proteins (sHSPs), SsHSP14.1, Sulfolobus solfataricus (S. solfataricus), EcoR I, salt bridge, oligomer

Abstract: SsHSP14.1, a novel sHSP from the hyper-thermophilic archaeon Sulfolobus solfataricus (S. solfataricus), is reported herein to function to protect EcoR I from heat-induced inactivation. A predicted salt bridge and hydrophobic interactions were found to be important for this function.

Cite this article as:

Zhenzhen Wen, Yonghua Wang, Xun Xu, Bo Yang, Wencheng Li and Mingquan Xie, “ Importance of a Potential Salt Bridge and Hydrophobic Core in the Function and Oligomerization of a Small Heat Shock Protein”, Protein & Peptide Letters (2010) 17: 751. https://doi.org/10.2174/092986610791190273

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