Drug Targets in Infections with Ebola and Marburg Viruses

Author(s): Olinger G. Gene, Biggins E. Julia, Melanson R. Vanessa, Wahl-Jensen Victoria, Geisbert W. Thomas, Hensley E. Lisa.

Journal Name: Infectious Disorders - Drug Targets
(Formerly Current Drug Targets - Infectious Disorders)

Volume 9 , Issue 2 , 2009

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Abstract:

The development of antiviral drugs for Ebola and Marburg viruses has been slow. To date, beyond supportive care, no effective treatments, prophylactic measures, therapies, or vaccines are approved to treat or prevent filovirus infections. In this review, we examine the current treatments available to administer care for filovirus infection, the potential therapeutic targets that can be used for filovirus drug development, and the various drug targeting techniques used against filoviruses.

Keywords: Filoviridae, Ebola virus, Marburg virus, drug targets, therapeutics, pathogenesis, pathology, immunotherapy

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Article Details

VOLUME: 9
ISSUE: 2
Year: 2009
Page: [191 - 200]
Pages: 10
DOI: 10.2174/187152609787847730
Price: $58

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