Abstract
In this work we aimed at finding a concise method for the design of the new pharmacologically active compound 6, which is a precursor to obtaining non-protein amino acid 7 considered as GABA analogue, furthermore it can be used to construct enantiopure, conformationally restricted peptides. For this purpose the Schmidt reaction was applied.
Keywords: Amino acids, schmidt reaction, natural products, terpenoids
Letters in Organic Chemistry
Title: Concise Synthesis of Non-Protein Amino Acid from Natural Product via Schmidt Reaction
Volume: 6 Issue: 3
Author(s): Kamila Gajcy, Tadeusz Librowski and Stanislaw Lochynski
Affiliation:
Keywords: Amino acids, schmidt reaction, natural products, terpenoids
Abstract: In this work we aimed at finding a concise method for the design of the new pharmacologically active compound 6, which is a precursor to obtaining non-protein amino acid 7 considered as GABA analogue, furthermore it can be used to construct enantiopure, conformationally restricted peptides. For this purpose the Schmidt reaction was applied.
Export Options
About this article
Cite this article as:
Gajcy Kamila, Librowski Tadeusz and Lochynski Stanislaw, Concise Synthesis of Non-Protein Amino Acid from Natural Product via Schmidt Reaction, Letters in Organic Chemistry 2009; 6 (3) . https://dx.doi.org/10.2174/157017809787893037
DOI https://dx.doi.org/10.2174/157017809787893037 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Characterization of the Early CNS Stress Biomarkers and Profiles Associated with Neuropsychiatric Diseases
Current Genomics Classical Neurotransmitters and Neuropeptides Involved in Parkinson's Disease: Focus on Anti-Parkinsonian Drugs
Current Drug Therapy Neurological Aspects of Medical Use of Cannabidiol
CNS & Neurological Disorders - Drug Targets Bioinformatic Screening of Autoimmune Disease Genes and Protein Structure Prediction with FAMS for Drug Discovery
Protein & Peptide Letters Future Directions for Pharmacotherapies for Treatment-resistant Bipolar Disorder
Current Neuropharmacology Glycaemic Control: A Balancing Act or A Different Approach?
Current Diabetes Reviews Transplantation of Stem Cells as a Potential Therapeutic Strategy in Neurodegenerative Disorders
Current Stem Cell Research & Therapy Nitric Oxide and Teratogenesis: An Update
Current Pharmaceutical Design In Silico Studies in Drug Research Against Neurodegenerative Diseases
Current Neuropharmacology Gap Junctions as Therapeutic Targets in Brain Injury Following Hypoxia- Ischemia
Recent Patents on CNS Drug Discovery (Discontinued) Bryostatin-1 Synergizes with Histone Deacetylase Inhibitors to Reactivate HIV-1 from Latency
Current HIV Research Probenecid: An Emerging Tool for Neuroprotection
CNS & Neurological Disorders - Drug Targets Biochemical Markers for Brain Injury Monitoring in Children with or without Congenital Heart Diseases
CNS & Neurological Disorders - Drug Targets Patent Selections:
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery Oral L-Carnitine: Metabolite Formation and Hemodialysis
Current Drug Metabolism Role of Mesenchymal Stem Cells in Dermal Repair in Burns and Diabetic Wounds
Current Stem Cell Research & Therapy Millennium Nutrient N,N-Dimethylglycine (DMG) and its Effectiveness in Autism Spectrum Disorders
Current Medicinal Chemistry Preparation of Tiagabine HCl/2-HPβCD Complex Pellets by Extrusion-Spheronization Using Glycerol Monostearate as Pellet-Aid
Letters in Drug Design & Discovery Machine Learning, Molecular Modeling, and QSAR Studies on Natural Products Against Alzheimer’s Disease
Current Medicinal Chemistry Central and Peripheral Pain Generators in Women with Chronic Pelvic Pain: Patient Centered Assessment and Treatment
Current Rheumatology Reviews